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Proteintech
KATNB1 Polyclonal Antibody
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产品信息
14969-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KATNB1 Fusion Protein Ag6836 (305-655 aa encoded by BC001353)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VTRTGTVAR DPVQDHRPLA QPLPNPSAPL RRIYERPSTT CSKPQRVKQN SESERRSPSS EDDRDERESR AEIQNAEDYN EIFQPKNSIS RTPPRRSEPF PAPPEDDAAT AKEAAKPSPA MDVQFPVPNL EVLPRPPVVA STPAPKAEPA IIPATRNEPI GLKASDFLPA VKIPQQAELV DEDAMSQIRK GHDTMCVVLT SRHKNLDTVR AVWTMGDIKT SVDSAVAIND LSVVVDLLNI VNQKASLWKL DLCTTVLPQI EKLLQSKYES YVQTGCTSLK LILQRFLPLI TDMLAAPPSV GVDISREERL HKCRLCYKQL KSISGLVKSK SGLSGRHGST FRELHLLMAS LD (305-655 aa encoded by BC001353)
靶标信息
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: katanin (80 kDa); katanin p80 (WD repeat containing) subunit B 1; katanin p80 (WD40-containing) subunit B 1; Katanin p80 subunit B1; Katanin p80 WD40 repeat-containing subunit B1; katanin p80 WD40-containing subunit B1; KATNB1; p80 katanin
基因别名: 2410003J24Rik; KAT; KATNB1; LIS6
UniProt ID: (Human) Q9BVA0, (Mouse) Q8BG40
Entrez Gene ID: (Human) 10300, (Mouse) 74187, (Rat) 291852
negative regulation of microtubule depolymerization
cell cycle
mitotic nuclear division
metabolic process
positive regulation of cell death
positive regulation of neuron projection development
positive regulation of microtubule depolymerization
microtubule severing
cell division
mitotic chromosome movement towards spindle pole
protein targeting
