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Invitrogen
KCNK18 (extracellular) Polyclonal Antibody
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KCNK18 (extracellular) Antibody (PA5-77636) in ICC/IF
Immunocytochemistry analysis of KCNK18 (extracellular) in paraformaldehyde-fixed and permeabilized mouse/rat neuroblastoma and dorsal root ganglion neuron. A) Samples were probed with KCNK18 (extracellular) polyclonal antibody (Product # PA5-77636) at a dilution of 1:50, and incubated with goat anti-rabbit-AlexaFluor-555 and Hoechst. Visible light images are shown in Panel B.
产品信息
PA5-77636
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)EAEENPELKKFLDD, corresponding to amino acid residues 62-75 of mouse K2P 18.1
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
靶标信息
TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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