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Invitrogen
KCNK2 Polyclonal Antibody
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产品信息
PA5-77605
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide DPKSAAQNSKPRLSFSTK(C), corresponding to residues 8-25 of human K2P 2.1 (TREK-1)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.
Reconstitute using 50 uL deionized water.
靶标信息
TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. As well, it is regulated by various neurotransmitters. It has been shown that alterations in the functioning, regulation, or both of the TREK-1 channel may alter mood. TREK-1 is also activated by volatile anesthetics and has been suggested to be an important target in the action of these drugs. Therefore, this particular K+ channel emerges as a potential innovative target for developing new therapeutic agents for anesthesiology and neurology, such as antidepressants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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