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Invitrogen
KCNMB2 Polyclonal Antibody
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KCNMB2 Antibody (PA5-87770) in WB
Western blot analysis of KCNMB2 in extracts of various cell lines. Samples were incubated with KCNMB2 Polyclonal antibody (Product # PA5-87770) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-87770
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 68-194 of human KCNMB2 (NP_0058231)
偶联物
形式
Liquid
浓度
1.24 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TLLRSYMQSV WTEESQCTLL NASITETFNC SFSCGPDCWK LSQYPCLQVY VNLTSSGEKL LLYHTEETIK INQKCSYIPK CGKNFEESMS LVNVVMENFR KYQHFSCYSD PEGNQKSVIL TKLYSSN; Positive Samples: Mouse kidney, Mouse brain, Mouse lung, Rat brain, Rat kidney; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BK channel subunit beta-2; BKbeta2; calcium-activated potassium channel beta 2; Calcium-activated potassium channel subunit beta-2; Calcium-activated potassium channel, subfamily M subunit beta-2; Charybdotoxin receptor subunit beta-2; K(VCA)beta-2; Maxi K channel subunit beta-2; potassium large conductance calcium-activated channel, subfamily M, beta member 2; Rbeta3; Slo-beta-2; Slo-beta2
基因别名: 2700049B16Rik; 3110031N04Rik; Kcmb2; Kcnmb2
UniProt ID: (Mouse) Q9CZM9, (Rat) Q811Q0
Entrez Gene ID: (Mouse) 72413, (Rat) 294961
