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产品信息
PA5-50692
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to residues near the N terminal of human potassium large conductance calcium-activated channel, subfamily M, beta member 4 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2.9 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636144 |
产品详细信息
The antibody detects endogenous levels of total KCNMB4 protein.
靶标信息
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: big potassium channel beta subunit 4; BK channel beta subunit 4; BK channel subunit beta-4; BKbeta4; Calcium-activated potassium channel subunit beta-4; Calcium-activated potassium channel, subfamily M subunit beta-4; Charybdotoxin receptor subunit beta-4; hbeta4; K(VCA)beta-4; KCMB4; large conductance calcium-dependent potassium ion channel beta 4 subunit; Maxi K channel subunit beta-4; MaxiK channel beta-subunit 4; potassium channel subfamily M regulatory beta subunit 4; potassium large conductance calcium-activated channel, subfamily M, beta member 4; Slo-beta-4; Slowpoke beta 4
基因别名: 1700058G18Rik; 2900045G12Rik; KCNMB4
UniProt ID: (Human) Q86W47, (Mouse) Q9JIN6
Entrez Gene ID: (Human) 27345, (Mouse) 58802
分子生物学功能:
voltage-gated ion channel
