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Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Delayed-rectifier K(+) channel alpha subunit 3; potassium voltage-gated channel delayed-rectifier protein S3; Potassium voltage-gated channel subfamily S member 3; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3; potassium voltage-gated channel, modifier subfamily S, member 3; Shab-related delayed-rectifier K+ channel alpha subunit 3; voltage-gated potassium channel protein Kv9.3; Voltage-gated potassium channel subunit Kv9.3
基因别名: KCNS3; KV9.3
UniProt ID: (Human) Q9BQ31, (Mouse) Q8BQZ8
Entrez Gene ID: (Human) 3790, (Mouse) 238076
分子生物学功能: voltage-gated ion channel