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The antibody detects endogenous levels of total KCTD16 protein.
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD16 (potassium channel tetramerisation domain containing 16), also known as BTB/POZ domain-containing protein KCTD16, is a 428 amino acid protein that contains one BTB (POZ) domain. An auxiliary subunit of GABAB R1 and GABAB R2, KCTD16 increases agonist potency and alters the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BTB/POZ domain-containing protein KCTD16; potassium channel tetramerisation domain containing 16; Potassium channel tetramerization domain-containing protein 16
基因别名: 4930434H12Rik; Gm1267; KCTD16; KIAA1317
UniProt ID: (Human) Q68DU8, (Mouse) Q5DTY9
Entrez Gene ID: (Human) 57528, (Mouse) 383348
分子生物学功能: scaffold/adaptor protein