Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Antibodies Inc
KChIP2b K+ Channel Monoclonal Antibody (K60/73)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
75-004
应用
建议稀释比
已发表文章
产品规格
种属反应
Dog,
Human,
Mouse,
Pig,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
K60/73
抗原
Fusion protein amino acids 1-252 (full length) of rat KChIP2b (accession number AAF81756) produced recombinantly in E. Coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
KChIP2b is an isoform of the Kv Channel-Interacting Protein 2 (KChIP2), which is a regulatory subunit that interacts with voltage-gated potassium (Kv) channels. This isoform modulates the biophysical properties of Kv channels, including their inactivation kinetics and surface expression, thereby influencing cardiac and neuronal excitability. Dysregulation of KChIP2b can impact heart function and has been implicated in conditions such as cardiac arrhythmias.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: A-type potassium channel modulatory protein 2; A-type potassium channel modulatory protein KCNIP2; Cardiac voltage-gated potassium channel modulatory subunit; KChIP2; Kv channel interacting protein 2; Kv channel-interacting protein; Kv channel-interacting protein 2; potassium channel auxiliary subunit KCHIP2; Potassium channel-interacting protein 2
基因别名: KCHIP2; KCNIP2
UniProt ID: (Human) Q9NS61, (Mouse) Q9JJ69, (Rat) Q9JM59
Entrez Gene ID: (Pig) 100037948, (Human) 30819, (Dog) 403598, (Mouse) 80906, (Rat) 56817
A-type (transient outward) potassium channel activity
calcium ion binding
protein binding
potassium channel regulator activity
ion channel binding
ER retention sequence binding
protein N-terminus binding
voltage-gated ion channel activity
potassium channel activity
identical protein binding
metal ion binding
transport
ion transport
potassium ion transport
regulation of ion transmembrane transport
clustering of voltage-gated potassium channels
potassium ion export
potassium ion transmembrane transport
membrane repolarization
regulation of potassium ion transmembrane transport
protein heterooligomerization
detection of calcium ion
muscle contraction
signal transduction
chemical synaptic transmission
regulation of heart contraction
cardiac conduction
regulation of cation channel activity
