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Invitrogen
KDEL Polyclonal Antibody
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KDEL Antibody (PA5-116311) in WB
Western Blot analysis of HDEL using the HDEL Polyclonal Antibody (Product # PA5-116311) at a 1:2000 dilution. Lane 1: Hela whole cell lysate, Lane 2: MCF-7 whole cell lysate, Lane 3: 293 whole cell lysate. Lysates/proteins were loaded at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution. Predicted band size : 25 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116311
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 185-211 amino acids from the C-terminal region of human KDELR1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 78 kDa glucose-regulated protein; 94 kDa glucose-regulated protein; Binding-immunoglobulin protein; BiP; Endoplasmic reticulum chaperone BiP; Endoplasmin; ER lumen protein-retaining receptor 1; gp96 homolog; GRP-78; GRP-94; Heat shock protein 70 family protein 5; Heat shock protein 90 kDa beta member 1; Heat shock protein family A member 5; Heat shock protein family C member 4; HSP70 family protein 5; Immunoglobulin heavy chain-binding protein; KDEL; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; Lys-Asp-Glu-Leu; Putative MAPK-activating protein PM23; RP23-446N16.1; Tumor rejection antigen 1
基因别名: ERD2.1; GRP78; GRP94; HSP90B1; HSPA5; HSPC4; KDELR1; TRA1
Entrez Gene ID: (Human) 7184, (Human) 3309, (Human) 10945
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