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Immunogen sequence: YFEKKRRRNN NNDEVNANNL EWLSSLWDWY TSYLFHPIAS FQNFPVESDW DEDPDLFLER LAFPDLWLHP LIPTDYIKNL PMWRFKCLGV QSE
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. [provided by RefSeq].
Protein Aliases: E3 ubiquitin-protein ligase RNF103; hKF-1; KF-1; RING finger protein 103; RING-type E3 ubiquitin transferase RNF103; Zfp-103; Zinc finger protein 103 homolog; zinc finger protein expressed in cerebellum
Gene Aliases: HKF-1; KF-1; KF1; RNF103; ZFP-103; ZFP103
UniProt ID: (Human) O00237
Entrez Gene ID: (Human) 7844