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Invitrogen
KHDC1 Polyclonal Antibody
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产品信息
PA5-56041
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RERNSRSGKT RCRSKRSEQS MDMGTSALSK KPWWTLPQNF HAPMVFHMEE DQEELIFGHG D
Highest antigen sequence identity to the following orthologs: Mouse - 33%, Rat - 38%.
靶标信息
KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability. KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs. KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KH homology domain-containing protein 1; MGC10818
基因别名: bA257K9.4; C6orf147; C6orf148; Em:AC019205.8; KHDC1; NDG1
UniProt ID: (Human) Q4VXA5
Entrez Gene ID: (Human) 80759
