FIGURE: 1 / 1
Peptide sequence: MVRTKADSVP GTYRKVVAAR APRKVLGSST SATNSTSVSS RKEHVLCNLI
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 85%; Pig: 93%; Rabbit: 85%; Rat: 85%
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
Protein Aliases: HCV NS5A-transactivated protein 9; Hepatitis C virus NS5A-transactivated protein 9; OEATC-1; Overexpressed in anaplastic thyroid carcinoma 1; PAF15; PCNA-associated factor; PCNA-associated factor of 15 kDa; PCNA-clamp-associated factor
Gene Aliases: KIAA0101; L5; NS5ATP9; OEATC; OEATC-1; OEATC1; p15(PAF); p15/PAF; p15PAF; PAF; PAF15; PCLAF
UniProt ID: (Human) Q15004
Entrez Gene ID: (Human) 9768