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Peptide sequence: TTIVNPKQPK ETPKSFSFDY SYWSHTSPED INYASQKQVY RDIGEEMLQH
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%; Yeast: 100%; Zebrafish: 79%
KIF1A is the motor for anterograde axonal transport of synaptic vesicle precursors.The protein encoded by this gene is a member of the kinesin family. This protein is highly similar to mouse heavy chain kinesin member 1A protein which is an anterograde motor protein that transports membranous organelles along axonal microtubules. It is thought that this protein may play a critical role in the development of axonal neuropathies resulting from impaired axonal transport. There are multiple polyadenylation sites found in this gene. Sequence Note: X90840.1 is a chimeric sequence. Only the ATSV region was propagated into this RefSeq record. [6/26/03, RefSeq staff]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Axonal transporter of synaptic vesicles; DKFZp686I2094; FLJ30229; hUnc-104; kinesin, heavy chain, member 1A, homolog of mouse; Kinesin-like protein KIF1A; MGC133285; MGC133286; Microtubule-based motor KIF1A; tmp_locus_27; Unc-104- and KIF1A-related protein
基因别名: ATSV; C2orf20; HSN2C; KIF1A; MRD9; SPG30; UNC104
UniProt ID: (Human) Q12756
Entrez Gene ID: (Human) 547
分子生物学功能: microtubule binding motor protein