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Proteintech
KIRREL2 Polyclonal Antibody
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产品信息
10890-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KIRREL2 Fusion Protein Ag1036 (1-219 aa encoded by BC007312)
偶联物
形式
Liquid
浓度
0.41 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MLRMRVPAL LVLLFCFRGR AGPSPHFLQQ PEDLVVLLGE GGAQASLGRR ASASFSEQKN LMRIPGSSDG SSSRGPEEEE TGSREDRGPI VHTDHSDLVL EEEGTLETKD PTNGYYKVRG VSVSLSLGEA PGGGLFLPPP SPLGPPGTPT FYDFNPHLGM VPPCRLYRAR AGYLTTPHPR AFTSYIKPTS FGPPDLAPGT PPFPYAAFPT PSHPRLQTHV (1-219 aa encoded by BC007312)
靶标信息
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp564A1164; Kin of IRRE-like protein 2; kin of irregular chiasm-like 2; Kin of irregular chiasm-like protein 2; MGC15718; nephrin-like 3; nephrin-like gene 1; Nephrin-like protein 3; X kin of IRRE like 2
基因别名: C330019F22Rik; FILTRIN; KIRREL2; NEPH3; NLG1; UNQ5827/PRO19646
UniProt ID: (Human) Q6UWL6, (Mouse) Q7TSU7
Entrez Gene ID: (Human) 84063, (Rat) 100359836, (Mouse) 243911
