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Proteintech
KIRREL3 Polyclonal Antibody
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产品信息
18055-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KIRREL3 Fusion Protein Ag12573 (28-381 aa encoded by BC101801)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: CLVLGYMAK DKFRRMNEGQ VYSFSQQPQD QVVVSGQPVT LLCAIPEYDG FVLWIKDGLA LGVGRDLSSY PQYLVVGNHL SGEHHLKILR AELQDDAVYE CQAIQAAIRS RPARLTVLVP PDDPVILGGP VISLRAGDPL NLTCHADNAK PAASIIWLRK GEVINGATYS KTLLRDGKRE SIVSTLFISP GDVENGQSIV CRATNKAIPG GKETSVTIDI QHPPLVNLSV EPQPVLEDNV VTFHCSAKAN PAVTQYRWAK RGQIIKEASG EVYRTTVDYT YFSEPVSCEV TNALGSTNLS RTVDVYFGPR MTTEPQSLLV DLGSDAIFSC AWTGNPSLTI VWMKRGSGVV LSNEK (28-381 aa encoded by B C101801)
靶标信息
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Kin of IRRE-like protein 3; Kin of irregular chiasm-like protein 3; membrane protein mKirre; mKirre; nephrin-like 2; Nephrin-like protein 2; X kin of IRRE like 3
基因别名: 1500010O20Rik; 2900036G11Rik; KIAA1867; KIRRE; KIRREL3; mKIAA1867; MRD4; NEPH2; PRO4502; SST4; UNQ5923/PRO4502/PRO19814
UniProt ID: (Human) Q8IZU9, (Mouse) Q8BR86
Entrez Gene ID: (Human) 84623, (Mouse) 67703, (Rat) 315546
