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Invitrogen
KIRREL3 Polyclonal Antibody
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KIRREL3 Antibody (PA5-48064) in WB
Western blot analysis of KIRREL3 in rat embryonic hippocampal neuron. Samples were incubated in KIRREL3 polyclonal antibody (Product # PA5-48064) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Sheep IgG secondary antibody. A specific band was detected for Kirrel3 at approximately 120 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
PA5-48064
产品规格
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human Kirrel3/NEPH2 Tyr33-Ala535
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, less than 3% cross-reactivity with recombinant human (rh) Kirrel1 and rhKirrel2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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