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Proteintech
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Immunogen sequence: MNIHMKRKT IKNINTFENR MLMLDGMPAV RVKTELLESE QGSPNVHNYP DMEAVPLLLN NVKGEPPEDS LSVDHFQTQT EPVDLSINKA RTSPTAVSSS PVSMTASASS PSSTSTSSSS SSRLASSPTV ITSVSSASSS STVLTPGPLV ASASGVGGQQ FLHIIHPVPP SSPMNLQSNK LSHVHRIPVV VQSVPVVYTA VRSPGNVNNT IVVPLLEDGR GHGKAQMDPR GLSPRQSKSD SDDDDLPNVT LDSVNETGST ALSIARAVQE VHPSPVSRVR GNRMNNQKFP CSISPFSIES TRRQRRSESP DSRKRRIHRC DFEGCNKVYT KSSHLKAHRR THTGEKPYKC TWEGCTWKFA RSDELTRHYR KHTGVKPFKC ADCDRSFSRS DHLALHRRRH MLV (1-402 aa encoded by BC019680)
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AP-2 repressor; AP-2rep transcription factor; BHLHB24; ID; KLF12 zinc finger transcriptional repressor; Krueppel-like factor 12; Kruppel-like factor 12; Transcriptional repressor AP-2rep
基因别名: AP-2rep; AP2REP; HSPC122; KLF12
UniProt ID: (Human) Q9Y4X4
Entrez Gene ID: (Human) 11278