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Proteintech
KLF5 Polyclonal Antibody
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产品信息
21017-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLF5 Fusion Protein Ag15267 (1-350 aa encoded by BC042131)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody detects the 50-60 kDa isoform 1 of KLF5. The antibody can recognize isoform 2 (33 kDa) and isoform 3 (18 kDa) too.
Immunogen sequence: MATRVLSMS ARLGPVPQPP APQDEPVFAQ LKPVLGAANP ARDAALFPGE ELKHAHHRPQ AQPAPAQAPQ PAQPPATGPR LPPEDLVQTR CEMEKYLTPQ LPPVPIIPEH KKYRRDSASV VDQFFTDTEG LPYSINMNVF LPDITHLRTG LYKSQRPCVT HIKTEPVAIF SHQSETTAPP PAPTQALPEF TSIFSSHQTA APEVNNIFIK QELPTPDLHL SVPTQQGHLY QLLNTPDLDM PSSTNQTAAM DTLNVSMSAA MAGLNTHTSA VPQTAVKQFQ GMPPCTYTMP SQFLPQQATY FPPSPPSSEP GSPDRQAEML QNLTPPPSYA ATIASKLAIH NPNLPTTLPV N (1-350 aa encoded by BC042131)
靶标信息
KLF5 is a member of the Kruppel-like factor subfamily of zinc finger proteins. It contains three C2H2-type zinc fingers at the carboxyl-terminus that preferentially bind to cis-DNA elements that are GC rich. KLF5 is a transcription activator that promotes cell proliferation and oncogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: (intestinal Kruppel-like factor; basic transcription element binding protein 2; basic transcription element binding protein BTEB2; Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; colon kruppel-like factor; GC box binding protein 2; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Klf5C isoform; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal); RP11-505F3.5; Transcription factor BTEB2
基因别名: 4930520J07Rik; BTEB2; CKLF; IKLF; KLF5
UniProt ID: (Human) Q13887, (Mouse) Q9Z0Z7
Entrez Gene ID: (Human) 688, (Rat) 84410, (Mouse) 12224
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
metal ion binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
sequence-specific DNA binding
nucleic acid binding
C2H2 zinc finger transcription factor
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
transcription from RNA polymerase II promoter
microvillus assembly
regulation of microvillus assembly
skeletal muscle cell differentiation
positive regulation of fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
intestinal epithelial cell development
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of transcription, DNA-templated
cellular response to organic cyclic compound
cellular response to peptide
transcription, DNA-templated
regulation of transcription, DNA-templated
