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Proteintech
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Immunogen sequence: MDVLASYSI FQELQLVHDT GYFSALPSLE ETWQQTCLEL ERYLQTEPRR ISETFGEDLD CFLHASPPPC IEESFRRLDP LLLPVEAAIC EKSSAVDILL SRDKLLSETC LSLQPASSSL DSYTAVNQAQ LNAVTSLTPP SSPELSRHLV KTSQTLSAVD GTVTLKLVAK KAALSSVKVR SLISAHGRDV SGVLHEAMSS RGTTGNTQVQ SPSNATTATG VFPGLTILPS T (1-230 aa encoded by BC012919)
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。