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Invitrogen
KLF9 Recombinant Superclonal Antibody (5HCLC)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 4
KLF9 Antibody (710921) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized A549 cells for detection of endogenous KLF9 using Anti-KLF9 Recombinant Rabbit Polyclonal Antibody (Product # 710921, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of KLF9 protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). P... View More
产品信息
710921
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
克隆号
5HCLC
抗原
Peptides corresponding to Human KLF9 (aa 34-49, 85-98)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2633101
产品详细信息
This antibody is predicted to react with Bovine, Pig and Monkey.
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
靶标信息
KLF-9 is a transcription factor belonging to the Sp 1 C2H2 type zinc finger family. It binds to GC box elements located in the promoter. This binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. KLF-9 serves as a key transcriptional regulator for uterine endometrial cell proliferation, adhesion, and differentiation both during pregnancy and tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: basic transcription element binding protein 1; Basic transcription element-binding protein 1; BTE-binding protein 1; GC-box-binding protein 1; Krueppel-like factor 9; Kruppel-like factor 9; Transcription factor BTEB1
基因别名: BTEB; BTEB1; KLF9
UniProt ID: (Human) Q13886, (Rat) Q01713
Entrez Gene ID: (Human) 687, (Rat) 117560
DNA binding
transcription factor activity, sequence-specific DNA binding
metal ion binding
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
nucleic acid binding
C2H2 zinc finger transcription factor
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
circadian rhythm
negative regulation of keratinocyte proliferation
cellular response to cortisol stimulus
cellular response to thyroid hormone stimulus
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
embryo implantation
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
progesterone receptor signaling pathway
cellular response to peptide
