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Invitrogen
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This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CUL3-interacting protein 1; FLJ27152; kelch-like 12; Kelch-like protein 12; kelch-like protein C3IP1
基因别名: C3ip1; Klhl12
UniProt ID: (Rat) Q8R2H4
Entrez Gene ID: (Rat) 266772