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Proteintech
KLRG1 Monoclonal Antibody (2F1)
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KLRG1 Antibody (65084-1-IG) in Flow
1X10^6 mouse splenocytes were surface stained with 0.5 µg Anti-Mouse KLRG1 (Product # 65084-1-IG, Clone: 2F1) and FITC anti-Golden Syrian Hamster IgG Antibody at dilution 1:50 (green), or stained with 0.5 µg Golden Syrian Hamster IgG isotype control and FITC anti-Golden Syrian Hamster IgG Antibody at dilution 1:50 (black). Cells were not fixed.
产品信息
65084-1-IG
产品规格
种属反应
Mouse
宿主/亚型
Hamster
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
2F1
抗原
Immunogen information and sequence are proprietary
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Wet ice
靶标信息
KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Killer cell lectin-like receptor subfamily G member 1; Mast cell function-associated antigen 2F1; natural killer cell receptor
基因别名: 2F1-Ag; Klrg1; MAFA; MAFA-L
UniProt ID: (Mouse) O88713
Entrez Gene ID: (Mouse) 50928
