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Progen
KRT2 Monoclonal Antibody (Ks2.342.7.4)
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产品信息
65191PROGEN
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
Ks2.342.7.4
抗原
Synthetic Peptide (N-Terminal Amino Acids Nos. 2-23) Of Human Keratin K2 (Mw 65,852)
偶联物
形式
Liquid
浓度
Conc. Not Determined
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Ks 2.342.7.4 represents an excellent marker to study terminal epidermal differentiation. The mab is reactive with epidermal cells in uppermost suprabasal layers including scalp, foot and sole. It recognizes individual cells within epidermis of tongue and mamille (co-localization with keratin K10). It is also reactive on hyperkeratosis of diverse viral and genetic origin.The mab does not react with palate keratin K76.The actual clone designation of this antibody is Ks2.342.7.4. The 2 last digits refer to the passage number of the cultured cells of clone Ks2.342. Passage 7.1 is used up. Reactive polypeptide (specificity): Basic human keratin K2 (MW 65,852; formerly also designated cytokeratin 2e).Antigen recognized in species:bovine: calf hoof epidermis, snooze epithelium; negative with tongue epithelium;Mouse/rat: heterogenously on foot sole epidermis only,negative with epidermis of other body sites. .
靶标信息
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK-2e; Cytokeratin-2e; Epithelial keratin-2e; K2e; keratin 2, type II; keratin 2e; Keratin, type II cytoskeletal 2 epidermal; Keratin-2 epidermis; Keratin-2e; MGC116967; MGC116968; Type-II keratin Kb2
基因别名: CK-2e; K2e; KRT2; KRT2A; KRT2E; KRTE
UniProt ID: (Human) P35908
Entrez Gene ID: (Human) 3849
