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产品信息
PA5-64866
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human KCND1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2664917 |
产品详细信息
Immunogen sequence: NTLDRYPDTLL GSSEKEFFYD ADSGEYFFDR DPDMFRHVLN FYRTGRLHCP RQECIQAFDE ELAFYGLVPE LVGDCCLEEY RDRKKENAER LAEDEEAEQ
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
靶标信息
The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1. 1, KV1. 2 and KV1. 4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: potassium channel, voltage gated Shal related subfamily D, member 1; Potassium voltage-gated channel subfamily D member 1; potassium voltage-gated channel, Shal-related subfamily, member 1; Shal-type potassium channel; Voltage-gated potassium channel subunit Kv4.1
基因别名: KCND1; KV4.1
UniProt ID: (Human) Q9NSA2
Entrez Gene ID: (Human) 3750
分子生物学功能:
voltage-gated ion channel
