Peptide sequence: CQAQQTISLA SSDPQKTVTM ILSAVHIQPF DIISDFVFSE EHKCPVDERE
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 82%
Lysosome-associated membrane protein 5 (LAMP5) is a member of the LAMP family. LAMP5 differs from other LAMP family members in that its expression is more restricted and is referred to as brain and dendritic cell-associated LAMP-like molecule (BAD-LAMP). In humans, BAD-LAMP is expressed in post-natal neurons and non-activated plasmacytoid dendritic cells. Expression in neurons is localized to intracellular vesicles distributed in specific microdomains along neurites and may play a role in endocytosis. BAD-LAMP is localized to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) of plasmacytoid dendritic cells and is lost upon TLR activation.
蛋白别名: BAD-LAMP; brain and dendritic cell associated LAMP; Brain and dendritic cell-associated LAMP; Brain-associated LAMP-like protein; LAMP family protein C20orf103; LAMP-5; lysosomal-associated membrane protein family, member 5; Lysosome-associated membrane glycoprotein 5; Lysosome-associated membrane protein 5
基因别名: BAD-LAMP; BADLAMP; C20orf103; LAMP-5; LAMP5; UNC-46
UniProt ID: (Human) Q9UJQ1
Entrez Gene ID: (Human) 24141