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Proteintech
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Immunogen sequence: TKRSITFLCG DAGPLAVAAV LYHKMNNEKQ AEDCITRLIH LNKIDPHAPN EMLYGRIGYI YALLFVNKNF GVEKIPQSHI QQICETILTS GENLARKRNF TAKSPLMYEW YQEYYVGAAH GLAGIYYYLM QPSLQVSQGK LHSLVKPSVD YVCQLKFPSG NYPPCIGDNR DLLVHWCHGA PGVIYMLIQA YKVFREEKYL CDAYQCADVI WQYGLLKKGY GLCHGSAGNA YAFLTLYNLT QDMKYLYRAC KFAEWCLEYG EHGCRTPDTP FSLFEGMAGT IYFLADLLVP TKARFPAFEL
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 40 kDa erythrocyte membrane protein; G protein-coupled receptor 69; G protein-coupled receptor 69A; Glutathione S-transferase LANCL1; LanC (bacterial lantibiotic synthetase component C)-like 1; LanC (bacterial lantibiotic synthetase component); LanC lantibiotic synthetase component C-like 1; LanC-like 1; LanC-like 1(bacterial); LanC-like protein 1; p40
基因别名: AW124738; Gpr69; GPR69A; LANCL1; p40
UniProt ID: (Human) O43813, (Rat) Q9QX69, (Mouse) O89112
Entrez Gene ID: (Pig) 100153701, (Human) 10314, (Rat) 114515, (Mouse) 14768