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Immunogen sequence: VRWDTFPLGR MPGQTEDPAE LMLENYDTMY LLDQPVLEQR LEPSTCKTDT LGLSCGVGSG NCSNSSSSNF EGLLWSQGQL HGLKTG
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 67%.
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endoribonuclease LAS1L; LAS1-like, ribosome biogenesis factor; Protein LAS1 homolog; Ribosomal biogenesis protein LAS1L
基因别名: dJ475B7.2; Las1-like; LAS1L; MSTP060
UniProt ID: (Human) Q9Y4W2
Entrez Gene ID: (Human) 81887