Search Thermo Fisher Scientific
Immunogen sequence: ITWFQNRRAKL KRDLEEMKAD VESAKKLGPS GQMDIVALAE LEQNSEATAG GGGGCGRAKS RPGSPVLPPG APKAPGAGAL QLSPASPLTD QPASSQDCSE DEEDEEIDVD
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 90%.
LBX1 is the transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: lady bird-like homeobox; ladybird homeobox homolog 1; Ladybird homeobox protein homolog 1; Transcription factor LBX1; transcription factor similar to D. melanogaster homeodomain protein lady bird late
基因别名: homeobox; HPX-6; HPX6; LBX1; LBX1H
UniProt ID: (Human) P52954
Entrez Gene ID: (Human) 10660
分子生物学功能: helix-turn-helix transcription factor homeodomain transcription factor DNA-binding transcription factor gene-specific transcriptional regulator