Peptide Sequence: TNHQIYELEK RFLYQKYLSP ADRDQIAQQL GLTNAQVITW FQNRRAKLKR DLEEMKADVE SAKKLGPSGQ MDIVALAELE QNSEATA
LBX1 is the transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.
蛋白别名: lady bird-like homeobox; ladybird homeobox homolog 1; Ladybird homeobox protein homolog 1; Transcription factor LBX1; transcription factor similar to D. melanogaster homeodomain protein lady bird late
基因别名: LBX1; LBX1H