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Invitrogen
LDOC1 Polyclonal Antibody
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产品信息
PA5-66429
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ISLLTGEAEEW VVPYIEMDSP ILGDYRAFLD EMKQCFGWDD DEDDD
Highest antigen sequence identity to the following orthologs - mouse 72%, rat 81%.
靶标信息
LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 7-Mar; breast cancer, up-regulated 1; Leucine zipper; leucine zipper downregulated in cancer; Leucine zipper protein down-regulated in cancer cells; leucine zipper, down-regulated in cancer 1; Protein LDOC1
基因别名: BCUR1; LDOC1; Mar7; Mart7
UniProt ID: (Human) O95751
Entrez Gene ID: (Human) 23641
