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Proteintech
LEFTY1 Recombinant Rabbit Monoclonal Antibody (240346E11)
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产品信息
83586-1-RR
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
240346E11
抗原
LEFTY1 fusion protein Ag4925
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence:
EQLLGSLLR QLQLKEVPTL DRADMEELVI PTHVRAQYVA LLQRSHGDRS RGKRFSQSFR EVAGRFLALE ASTHLLVFGM EQRLPPNSEL VQAVLRLFQE PVPKAALHRH GRLSPRSARA RVTVEWLRVR DDGSNRTSLI DSRLVSVHES GWKAFDVTEA VNFWQQLSRP RQPLLLQVSV QREHLGPLAS GAHKLVRFAS QGAPAGLGEP QLELHTLDLG DYGAQGDCDP EAPMTEGTRC CRQEMYIDLQ GMKWAENWVL EPPGFLAYEC VGTCRQPPEA LAFKWPFLGP RQCIASETDS LPMIVSIKEG GRTRPQVVSL PNMRVQKCSC ASDGALVPRR LQP
靶标信息
This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Left-right determination factor 1; Left-right determination factor B; left-right determination, factor B; Lefty protein; Protein lefty-1; Protein lefty-B; Stimulated by retinoic acid gene 3 protein; TGF-beta-4; Transforming growth factor beta-4
基因别名: AI450052; Ebaf; LEFTB; Lefty; lefty-1; LEFTY1; LEFTYB; RGD1561867; Stra3; Tgfb4; UNQ278/PRO317
UniProt ID: (Human) O75610, (Mouse) Q64280
Entrez Gene ID: (Human) 10637, (Rat) 498299, (Mouse) 13590
negative regulation of transcription from RNA polymerase II promoter
heart morphogenesis
transforming growth factor beta receptor signaling pathway
determination of left/right symmetry
positive regulation of pathway-restricted SMAD protein phosphorylation
cell growth
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
negative regulation of cell proliferation
anterior/posterior axis specification
response to retinoic acid
cell migration involved in gastrulation
negative regulation of nodal signaling pathway
negative regulation of nodal receptor complex assembly
multicellular organism development
growth
