Search Thermo Fisher Scientific
Immunogen sequence: MADMEDLFG SDADSEAERK DSDSGSDSDS DQENAASGSN ASGSESDQDE RGDSGQPSNK ELFGDDSEDE GASHHSGSDN HSERSDNRSE ASERSDHEDN DPSDVDQHSG SEAPNDDEDE GHRSDGGSHH SEAEGSEKAH SDDEKWGRED KSDQSDDEKI QNSDDEERAQ GSDEDKLQNS DDDEKMQNTD DEERPQLSDD ERQQLSEEEK ANSDDERPVA SDNDDEKQNS DDEEQPQLSD EEKMQNSDDE RPQASDEEHR HSDDEEEQDH KSESARGSDS EDEVLRMKRK NAIASDSEAD SDTEVPKDNS GTMDLFGGAD DISSGSDGED KPP (1-332 aa encoded by BC018147)
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Leo1 Paf1/RNA polymerase II complex component; Leo1, Paf1/RNA polymerase II complex component, homolog; Replicative senescence down-regulated leo1-like protein; RNA polymerase-associated protein LEO1
基因别名: Gm185; LEO1; RDL
UniProt ID: (Human) Q8WVC0, (Rat) Q641X2, (Mouse) Q5XJE5
Entrez Gene ID: (Human) 123169, (Rat) 300837, (Mouse) 235497
分子生物学功能:
DNA-directed RNA polymerase
RNA metabolism protein
nucleic acid metabolism protein