Invitrogen

LEPREL2 Polyclonal Antibody

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LEPREL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of LEPREL2 in paraffin embedded Human rectal cancer tissue using LEPREL2 Polyclonal Antibody (Product # PA5-50439) at a 1:50 dilution.

产品信息

PA5-50439

应用	建议稀释比	已发表文章
免疫印迹 (WB)	1:500-1:2,000	-
免疫组化（石蜡） (IHC (P))	1:50-1:200	-

产品规格
种属反应	Human, Mouse
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	Fusion protein corresponding to a region derived from internal residues of human leprecan-like 2
偶联物	Unconjugated
形式	Liquid
浓度	2.2 mg/mL
纯化类型	Antigen affinity chromatography
保存液	PBS, pH 7.4, with 40% glycerol
内含物	0.05% sodium azide
保存条件	-20°C
RRID	AB_2635892

产品详细信息

The antibody detects endogenous levels of total LEPREL2 / P3H3 protein.

靶标信息

The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.

仅用于科研。不用于诊断过程。未经明确授权不得转售。