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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GHLPKPTLWA EPGSVIIQGS PVTLRCQGSL QAEEYHLYRE NKSASWVRRI QEPGKNGQFP IPSITWEHAG RYHCQYYSHN HSSEYSDPLE LVVTGAYSKP TLSALPSPVV TSGGNVTLQC VSQVAFDGFI LCKEGEDEHP QRLNSHSHAR GWSWAIFSVG PVSPSRRWSY RCYAYDSNSP YVWSLPSDLL ELLVPGVSKK PSLSVQPGPM VAPGESL
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (LILRB1; MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with trans membrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD85 antigen-like family member H; CD85h; ILT-1; Immunoglobulin-like transcript 1; Leukocyte immunoglobulin-like receptor 7; Leukocyte immunoglobulin-like receptor subfamily A member 2; LIR-7
基因别名: ILT1; LILRA2; LIR7
Entrez Gene ID: (Human) 11027