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产品信息
PA5-61961
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human CD85g (ILT7)
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2639548
产品详细信息
Immunogen sequence: DHRLSWTLNS HQHNHGKFQA LFPMGPLTFS NRGTFRCYGY ENNTPYVWSE PSD
Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 52%.
靶标信息
ILT7 is a pDC-specific IgG-like transcript and is a member of the leukocyte immunoglobulin-like receptor gene family. This receptor, in complex with FcER1a, transduces ITAM-mediated signals which negatively modulate type I IFN production by pDC. ILT7 is thus a potential target to regulate Type 1 IFN production by pDC, which play a major role during viral infection, auto-immune diseases and anti-cancer immunity. Additionally, ILT7, along with CD123 and BDCA-2, can be used to identify or classify subsets of pDCalong with TLR expression and TLR mediated immune responses.
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生物信息学
蛋白别名: CD85 antigen-like family member G; CD85g; ILT-7; Immunoglobulin-like transcript 7; leucocyte Ig-like receptor A4; Leukocyte immunoglobulin-like receptor subfamily A member 4; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4
基因别名: CD85g; ILT7; LILRA4
UniProt ID: (Human) P59901
Entrez Gene ID: (Human) 23547
分子生物学功能:
immunoglobulin receptor superfamily
