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Proteintech
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Immunogen sequence: CVQAGTLPK PTLWAEPASV IARGKPVTLW CQGPLETEEY RLDKEGLPWA RKRQNPLEPG AKAKFHIPST VYDSAGRYRC YYETPAGWSE PSDPLELVAT GFYAEPTLLA LPSPVVASGG NVTLQCDTLD GLLTFVLVEE EQKLPRTLYS QKLPKGPSQA LFPVGPVTPS CRWRFRCYYY YRKNPQVWSN PSDLLEILVP GVSRKPSLLI PQGSVVARGG SLTLQCRSDV GYDIFVLYKE GEHDLVQGSG QQPQAGLSQA NFTLGPVSRS HGGQYRCYGA HNLSPRWSAP SDPLDILIAG LIPDIPALSV QPGPKVASGE NVTLLCQSWH QI (20-350 aa encoded by BC025704)
This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD85 antigen-like family member C; CD85c; leucocyte Ig-like receptor B5; Leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5; LIR-8
基因别名: CD85C; LILRB5; LIR-8; LIR8
UniProt ID: (Human) O75023
Entrez Gene ID: (Human) 10990