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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • LIM1 Antibodies

          Invitrogen

          LIM1 Polyclonal Antibody

          查看其他27个LIM1抗体

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          说明书
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          Cite LIM1 Polyclonal Antibody

          LIM1 Polyclonal Antibody

          产品信息

          PA5149644

          应用
          建议稀释比
          已发表文章

          免疫细胞化学 (ICC/IF)

          0.25-2 µg/mL
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          Recombinant protein corresponding to Human LHX1
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          0.05 mg/mL

          纯化类型

          Antigen affinity chromatography

          保存液

          PBS, pH 7.2, with 40% glycerol

          内含物

          0.02% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3709632

          产品详细信息

          Immunogen sequence: NGPFSFYGDY QSEYYGPGGN YDFFPQGPPS SQAQTPVDLP FVPSSGPSGT PLGGLEHPLP GHHPSSEAQR FTDILAHPPG DSPSPEPSLP GPLHSMSAEV FGPSPPFSSL SVNGGASYGN HL

          Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

          靶标信息

          This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of neural and lymphoid cells. A similar protein in mice is an essential regulator of the vertebrate head organizer.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: hLim-1; Homeobox protein Lim-1; LHX-1; LIM homeobox protein 1; LIM/homeobox protein Lhx1; MGC126723; MGC138141

          查看更多 收起

          基因别名: LHX1; LIM-1; LIM1

          查看更多 收起

          UniProt ID: (Human) P48742

          查看更多 收起

          Entrez Gene ID: (Human) 3975

          查看更多 收起

          功能
          transcription factor activity, sequence-specific DNA binding transcription corepressor activity zinc ion binding sequence-specific DNA binding helix-turn-helix transcription factor homeodomain transcription factor DNA-binding transcription factor gene-specific transcriptional regulator
          参与通路
          urogenital system development ureteric bud development branching involved in ureteric bud morphogenesis gastrulation with mouth forming second ectoderm formation endoderm formation kidney development transcription from RNA polymerase II promoter cell-cell signaling pattern specification process nervous system development motor neuron axon guidance anatomical structure morphogenesis post-embryonic development embryonic pattern specification organ morphogenesis anterior/posterior axis specification anterior/posterior pattern specification dorsal/ventral pattern formation regulation of gene expression retina layer formation ventral spinal cord development spinal cord association neuron differentiation telencephalon development cerebellum development cerebellar Purkinje cell differentiation forebrain regionalization cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation somite rostral/caudal axis specification metanephric part of ureteric bud development oviduct epithelium development uterine epithelium development nephric duct elongation horizontal cell localization positive regulation of embryonic development cellular response to fibroblast growth factor stimulus negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated anatomical structure formation involved in morphogenesis embryonic viscerocranium morphogenesis pronephros development embryonic retina morphogenesis in camera-type eye uterus development oviduct development cervix development vagina development head development epithelium development paramesonephric duct development comma-shaped body morphogenesis S-shaped body morphogenesis renal vesicle morphogenesis mesonephric duct development nephric duct morphogenesis metanephric glomerulus development metanephric comma-shaped body morphogenesis metanephric renal vesicle morphogenesis metanephric S-shaped body morphogenesis primitive streak formation positive regulation of branching involved in ureteric bud morphogenesis lateral motor column neuron migration positive regulation of gastrulation positive regulation of anterior head development positive regulation of nephron tubule epithelial cell differentiation
          It has to be done as per old AB suggested Products section.
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