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Invitrogen
LMBRD1 Polyclonal Antibody
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产品信息
PA5-90773
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human LMBRD1 (NP_0608383)
偶联物
形式
Liquid
浓度
1.39 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PLNLIKGTRS AAYERLENTE DIEEVEQHIQ TIKSKSKDGR PLPARDKRAL KQFEERLRTL KKRERHLEFI ENSWWTKFCG A; Positive Samples: U-87MG, HeLa, Mouse brain, Mouse lung, Mouse spleen; Cellular Location: Lysosome membrane, Multi-pass membrane protein
靶标信息
LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HDAg-L-interacting protein NESI; hepatitis delta antigen-L interacting protein; liver regeneration p-53 related protein; LMBD1; LMBR1 domain-containing protein 1; Lysosomal cobalamin transport escort protein LMBD1; Nuclear export signal-interacting protein; probable lysosomal cobalamin transporter; Protein N90b
基因别名: 0910001K20Rik; AV347960; BM-021; C6orf209; CD001; LMBD1; LMBRD1; MAHCF; MSTP044; NESI
UniProt ID: (Human) Q9NUN5, (Mouse) Q8K0B2
Entrez Gene ID: (Human) 55788, (Mouse) 68421
