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Product Details
MA5-17110
Applications
Tested Dilution
Publications
产品规格
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
4D8
Immunogen
Purified recombinant fragment of human LMO2 (amino acids: 1-158) expressed in E. Coli.
Conjugate
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2538581
Product Specific Information
MA5-17110 targets LMO2 in FACS, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17110 immunogen is purified recombinant fragment of human LMO2 (amino acids: 1-158) expressed in E. Coli.
MA5-17110 detects LMO2 which has a predicted molecular weight of approximately 18.4kDa.
Target Information
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Bioinformatics
Protein Aliases: Cysteine-rich protein TTG-2; LIM domain only 2 (rhombotin-like 1); LIM domain only protein 2; LMO-2; rhombotin 2; Rhombotin-2; rhombotin-like 1; T-cell translocation gene 2; T-cell translocation protein 2
Gene Aliases: LMO2; RBTN2; RBTNL1; RHOM2; TTG2
UniProt ID: (Human) P25791
Entrez Gene ID: (Human) 4005
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
zinc ion binding
bHLH transcription factor binding
cofactor binding
E-box binding
Performance Guarantee
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