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Product may be used with Western Blot (Cell lysate).
Immunogen sequence: VLVNGGLTPP KSEDKVSENG GLRFPRNTER PPETGPWRAP GPWEKTPESW GPAPTIGEPA PETSLERAPA PSAVVSSRNG GETAPGPLGP APKNGTLEPG
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: KIAA1883; protein phosphatase 1, regulatory subunit 101
基因别名: LMR3; PPP1R101; TYKLM3
Entrez Gene ID: (Human) 114783