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Invitrogen
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Immunogen sequence: KRVNAAFYRL LAQRQQHSFG LHGVACVGTE AHLSLCSLEF YRANDTARCP
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。