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Invitrogen
LPHN2 Monoclonal Antibody (1030202)
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产品信息
MA5-60896
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
1030202
抗原
Human Latrophilin 2/LPHN2 synthetic peptide
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adhesion G protein-coupled receptor L2; Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; Cl2aa; latrophilin 2; Latrophilin homolog 1; Latrophilin-2; Lectomedin-1
基因别名: ADGRL2; CIRL2; CL2; KIAA0786; LEC1; LPHH1; LPHN2
UniProt ID: (Human) O95490
Entrez Gene ID: (Human) 23266
