Invitrogen

LPXN Polyclonal Antibody

Name: LPXN Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-66394

高级验证

查看其他7个Leupaxin抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (3)
高级验证 (1)

LPXN Antibody in Immunocytochemistry (ICC/IF)

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LPXN Antibody (PA5-66394) in ICC/IF

Immunofluorescent staining of LPXN in human cell line U-2 OS shows localization to nuclear speckles, cytosol and focal adhesion sites. Samples were probed using a LPXN Polyclonal Antibody (Product # PA5-66394).

Product Image Gallery

LPXN Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of LPXN was observed specifically in PC-3 cells and in Caco-2 cells using anti-LPXN Polyclonal Antibody (Product # PA5-66394) in western blot. The relative expression levels of LPXN within each cell line is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image LPXN Polyclonal Antibody

产品信息

PA5-66394

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human LPXN. Recombinant protein control fragment (Product #RP-105187).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2662178

产品详细信息

Immunogen sequence: EELDALLEELE RSTLQDSDEY SNPAPLPLDQ HSRKETNLDE TSEILSIQ

Highest antigen sequence identity to the following orthologs - mouse 61%, rat 59%.

靶标信息

The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。