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Proteintech
LRDD Polyclonal Antibody
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产品信息
12119-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LRDD Fusion Protein Ag2761 (1-350 aa encoded by BC014904)
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAATVEGPE LEAAAAAGDA SEDSDAGSRA LPFLGGNRLS LDLYPGGCQQ LLHLCVQQPL QLLQVEFLRL STHEDPQLLE ATLAQLPQSL SCLRSLVLKG GQRRDTLGAC LRGALTNLPA GLSGLAHLAH LDLSFNSLET LPACVLQMRG LGALLLSHNC LSELPEALGA LPALTFLTVT HNRLQTLPPA LGALSTLQRL DLSQNLLDTL PPEIGGLGSL LELNLASNRL QSLPASLAGL RSLRLLVLHS NLLASVPADL ARLPLLTRLD LRDNQLRDLP PELLDAPFVR LQGNPLGEAS PDAPSSPVAA LIPEMPRLFL TSDLDSFPVT PRGCSVTLAC GVRLQFPAGA T (1-350 aa encoded by BC014904)
靶标信息
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DKFZp434D229; leucine-rich and death domain containing; Leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; MGC16925; p53 protein induced, with death domain; p53-induced death domain-containing protein 1; p53-induced protein with a death domain
基因别名: 1200011D09Rik; AU042446; LRDD; PIDD; PIDD1
UniProt ID: (Human) Q9HB75, (Mouse) Q9ERV7
Entrez Gene ID: (Human) 55367, (Mouse) 57913, (Rat) 293625
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
signal transduction
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of NF-kappaB transcription factor activity
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway
