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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LDDNELIQFPC KIGQLINLRF LSAARNKLPF LPSEFRNLSL EYLDLFGNTF EQPKVLPVIK LQAPLTLLES SART
Highest antigen sequence identity to the following orthologs - mouse 76%, rat 72%.
May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 4-1BB-mediated-signaling molecule; 4-1BBlrr; Leucine-rich repeat protein 1; LRR-1; LRR-repeat protein 1; Peptidylprolyl isomerase-like 5
基因别名: LRR1; PPIL5
Entrez Gene ID: (Human) 122769