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Invitrogen
LRRC8B Polyclonal Antibody
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LRRC8B Antibody (PA5-112101) in WB
Western Blot analysis of LRRC8B using LRRC8B Polyclonal Antibody (Product # PA5-112101) at a dilution of 1:500. Lane A: NCI-H292 whole cell lysate, (Lysates/proteins at 30 µg per lane). The secondary antibody used was a Goat Anti-Rabbit IgG (H&L)/Dylight 800 at 1:10,000 dilution. Developed using the Odyssey technique and performed under reducing conditions. Predicted band size: 92 kDa. Observed band size: 92 kDa.
产品信息
PA5-112101
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the center region of the Human LRRC8B
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody reacts with: Human, Mouse (Species predicted to react based on 100% sequence homology).
靶标信息
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: leucine rich repeat containing 8 family, member B; leucine-rich repeat containing 8 family member B; Leucine-rich repeat-containing protein 8B; T cell activation leucine repeat rich protein; T-cell activation leucine repeat-rich protein; TA-LRRP; Volume-regulated anion channel subunit LRRC8B
基因别名: KIAA0231; LRRC8B; TA-LRRP; TALRRP; UNQ6413/PRO21207
UniProt ID: (Human) Q6P9F7
Entrez Gene ID: (Human) 23507
