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Proteintech
LRRC8C Polyclonal Antibody
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产品信息
21601-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LRRC8C Fusion Protein Ag16213 (618-803 aa encoded by BC113973)
偶联物
形式
Liquid
浓度
0.47 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: DLKENNLKS IEEIVSFQHL RKLTVLKLWH NSITYIPEHI KKLTSLERLS FSHNKIEVLP SHLFLCNKIR YLDLSYNDIR FIPPEIGVLQ SLQYFSITCN KVESLPDELY FCKKLKTLKI GKNSLSVLSP KIGNLLFLSY LDVKGNHFEI LPPELGDCRA LKRAGLVVED ALFETLPSDV REQMKTE (618-803 aa encoded by BC113973 )
靶标信息
LRRC8C is a protein coding gene. Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Factor for adipocyte differentiation 158; hypothetical protein AD158; leucine rich repeat containing 8 family, member C; leucine rich repeat containing 8C; leucine-rich repeat containing 8 family member C; Leucine-rich repeat-containing protein 8C; Volume-regulated anion channel subunit LRRC8C
基因别名: AD158; AI326115; E430036I04Rik; FAD158; LRRC8C; RGD1306585
UniProt ID: (Human) Q8TDW0, (Mouse) Q8R502, (Rat) Q498T9
Entrez Gene ID: (Human) 84230, (Mouse) 100604, (Rat) 289443
