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Invitrogen
LRRC8C Polyclonal Antibody
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产品信息
PA5-56118
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human LRRC8C
偶联物
形式
Liquid
浓度
0.05 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: LERLSFSHNK IEVLPSHLFL CNKIRYLDLS YNDIRFIPPE IGVLQSLQYF SITCNKVESL PDELYFCKKL KTLKIGKNSL SVLSPKIGNL LFLSYLDVKG NHFEILPPEL GDCRALKRAG LVVEDALFET L
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
靶标信息
LRRC8C is a protein coding gene. Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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