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Proteintech
LRRC8C Monoclonal Antibody (4A6A4)
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产品信息
68323-1-IG
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
4A6A4
抗原
Recombinant protein
偶联物
形式
Liquid
纯化类型
Protein A
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: DLKENNLKSI EEIVSFQHLR KLTVLKLWHN SITYIPEHIK KLTSLERLSF SHNKIEVLPS HLFLCNKIRY LDLSYNDIRF IPPEIGVLQS LQYFSITCNK VESLPDELYF CKKLKTLKIG KNSLSVLSPK IGNLLFLSYL DVKGNHFEIL PPELGDCRAL KRAGLVVEDA LFETLPSDVR EQMKTE
靶标信息
LRRC8C is a protein coding gene. Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Factor for adipocyte differentiation 158; hypothetical protein AD158; leucine rich repeat containing 8 family, member C; leucine rich repeat containing 8C; leucine-rich repeat containing 8 family member C; Leucine-rich repeat-containing protein 8C; Volume-regulated anion channel subunit LRRC8C
基因别名: AD158; FAD158; LRRC8C
UniProt ID: (Human) Q8TDW0
Entrez Gene ID: (Human) 84230
