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Proteintech
LSM11 Polyclonal Antibody
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产品信息
26119-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LSM11 Fusion Protein Ag23281 (1-360 aa encoded by BC126449)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MEERERGAR SAGAGSPARP PSPRLDVSSD SFDPLLALYA PRLPPIPYPN APCFNNVAEY ESFLRTGVRG GGRGRGRARG AAAGSGVPAA PGPSGRTRRR PDAPAPDPER IQRLRRLMVA KEEGDGAAGA GRRGPGRSRK APRNVLTRMP LHEGSPLGEL HRCIREGVKV NVHIRTFKGL RGVCTGFLVA FDKFWNMALT DVDETYRKPV LGKAYERDSS LTLTRLFDRL KLQDSSKKEA DSKSAVEDST LSRYSQTSTW KLASVWGRAD TGRGSHKRSR SVPSSLQASA REESRSELSG RTTRTDGSSV GGTFSRATTL SRGQSRKKKR KPKVDYQQVF TRHINQIFIR GENVLLVHLA Q (1-360 aa encoded by BC126449)
靶标信息
LSm11 is a 360 amino acid protein that localizes to the nucleus and belongs to the LSm subfamily of snRNP Sm proteins. Containing an N-terminal domain that is necessary for pre-mRNA cleavage, LSm11 functions to binds specifically to U7 snRNA and is thought to play a role in cell cycle regulation and cell growth. The gene encoding LSm11 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ38273; U7 snRNA-associated Sm-like protein LSm11
基因别名: LSM11
UniProt ID: (Human) P83369
Entrez Gene ID: (Human) 134353
